Adrenaline fatigue: fact or myth?

Adrenal Fatigue: a myth or a fact?

The term has been used by doctors, healthcare providers, and the general media to describe an alleged condition caused by chronic exposure to stressful situations. Despite this, adrenal fatigue has not been recognized by any Endocrinology society, who claim there is no hard evidence for the existence.

A new systematic review tried to verify whether there is substantiation for “adrenal fatigue” using 58 studies . A systematic review is the highest level of evidence a study can have, and analyses all the research in the area to find the answer. 

This systematic review found that there is no proof or demonstration of the existence of “adrenal fatigue”. While a significant number of the reported studies showed differences between the healthy and fatigued groups, important methodological issues and confounding factors were apparent.

The authors concluded that due to the lack of substantiation that “adrenal fatigue” is an actual medical condition, is should therefore be considered as a myth.

Reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997656/